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Breztri Aerosphere 160 Mcg-9Mcg-4.8Mcg/Actuation HFA Aerosol Inhaler Orally Inhaled Steroids - Uses, Side Effects, And More

Read the Patient Information Leaflet and Instructions for Use if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Follow the instructions for priming the inhaler if you are using it for the first time, if you have not used it for a week or more, if you dropped the inhaler, or if you put the canister back into the inhaler after cleaning. When priming the inhaler, make sure to spray away from your face so that you do not get the medication into your eyes.

Shake the inhaler well before using. Inhale this medication by mouth as directed by your doctor, usually twice daily (in the morning and in the evening). Wait at least 1 minute between inhalations.

To prevent dry mouth, hoarseness, and oral yeast infections from developing, gargle, rinse your mouth with water and spit out after each use. Do not swallow the rinse water.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.

Do not increase your dose, use this medication more often, or stop using it without first consulting your doctor. Your condition will not improve any faster, and your risk of side effects will increase.

If you are using other inhalers at the same time, wait at least 1 minute between the use of each medication.

If you are regularly using a different corticosteroid taken by mouth (such as prednisone), you should not stop using it unless directed by your doctor. You may have withdrawal symptoms if the drug is suddenly stopped. Some conditions (such as asthma, allergies) may become worse when the drug is suddenly stopped. To prevent withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness), your doctor may direct you to slowly lower the dose of your old medication after you begin using this product. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away. See also Precautions section.

If you have been using a quick-relief inhaler (such as albuterol, also called salbutamol in some countries) on a regular daily schedule (such as 4 times daily), you must stop this schedule and only use the quick-relief inhaler as needed for sudden shortness of breath. Consult your doctor for details.

Learn which of your inhalers you should use every day and which you should use if your breathing suddenly worsens (quick-relief drugs). Ask your doctor ahead of time what you should do if you have new or worsening cough or shortness of breath, wheezing, increased sputum, waking up at night with trouble breathing, if you use your quick-relief inhaler more often, or if your quick-relief inhaler does not seem to be working well. Learn when you can treat sudden breathing problems by yourself and when you must get medical help right away.

Tell your doctor if your condition does not get better or if it gets worse.

What Kind Of High Is Delta 8?

Disclaimer: This post contains affiliate links. 

Curious about the kind of high Delta 8 can offer? Look no further! Derived from hemp, Delta 8 is a cannabinoid that packs a punch. With its psychoactive properties, it delivers a milder high compared to its cousin, Delta 9 THC. This makes it an appealing choice for many users seeking a more manageable experience. Described as both uplifting and relaxing, the high from Delta 8 strikes the perfect balance for those looking to unwind without feeling overwhelmed. So if you're searching for an alternative that offers a unique high, keep reading to discover what Delta 8 has in store for you.

Recommended Delta 8 Products

Everest Delta 8 Gummies

Budpop Delta 8 Gummies

Exhale Wellness Delta 8 Gummies

3CHI Delta 8 Gummies

Otterspace Delta 8 Gummies

The Mind-Altering Effects of Delta THC: What to Expect

Delta THC, also known as delta-8-tetrahydrocannabinol, is a compound found in cannabis that can produce various mind-altering effects. When consumed, delta-8-THC interacts with the body's endocannabinoid system, resulting in a range of sensations and experiences.

Euphoria, Relaxation, and Altered Perception of Time

One of the primary effects of delta 8 is its ability to induce euphoria and relaxation. Users often report feeling a sense of calmness and contentment after consuming this compound. It can provide a gentle and mellow high compared to its more potent counterpart, delta-9-THC.

In addition to euphoria and relaxation, delta 8 can also alter one's perception of time. Many users describe experiencing time dilation or a slowed perception of events. Minutes may feel like hours, allowing for a heightened appreciation of the present moment.

Heightened Sensory Perception and Increased Creativity

Another notable effect of delta THC is its potential to enhance sensory perception. Colors may appear more vibrant, sounds more vivid, and tastes more intense. This heightened sensory experience can lead to an increased appreciation for art, music, or even everyday activities like cooking or going for a walk.

Furthermore, some users report that delta 8 stimulates their creativity. Ideas flow more freely while engaging in creative pursuits such as writing or painting. This boost in imagination can be particularly appealing for individuals seeking inspiration or looking to tap into their artistic side.

Short-Term Memory Impairment and Dry Mouth

While there are many positive effects associated with delta 8 usage, it's important to note that it can also have some negative side effects. One common issue reported by users is short-term memory impairment. This can manifest as forgetfulness or difficulty recalling recent events. It's advisable to avoid engaging in activities that require sharp memory skills while under the influence of delta 8.

A dry mouth, also known as "cottonmouth," is a frequently reported side effect. Delta 8 can reduce saliva production, leading to feelings of thirst and a dry sensation in the mouth. Staying hydrated by drinking water or other fluids can help alleviate this discomfort.

The Science Behind Delta THC's Psychoactive Properties

Delta THC, also known as delta-8-tetrahydrocannabinol, is a fascinating compound that has gained significant attention in recent years. This cannabinoid, found in cannabis plants, offers a unique and distinct high compared to its more well-known counterpart, delta-9-tetrahydrocannabinol (delta-9-THC). Understanding the science behind delta THC's psychoactive properties can shed light on why it produces such a different experience. Let's delve into the intricacies of this compound.

1. Delta THC interacts with the endocannabinoid system in the brain, specifically targeting CB1 receptors.

The endocannabinoid system (ECS) plays a crucial role in regulating various physiological processes within our bodies. It consists of receptors, endocannabinoids produced by our bodies, and enzymes responsible for their synthesis and breakdown. When delta THC enters our system, it binds primarily to CB1 receptors located predominantly in the brain.

2. Its psychoactive effects are due to its ability to modulate neurotransmitter release in the brain.

Delta THC's interaction with CB1 receptors leads to the modulation of neurotransmitter release in the brain. Neurotransmitters are chemical messengers responsible for transmitting signals between nerve cells. By influencing their release, delta THC affects communication within different regions of the brain, resulting in altered perception and mood.

This modulation of neurotransmitters contributes to delta THC's psychoactive effects by impacting key systems involved in cognition, memory formation, and emotional responses. The specific mechanisms through which this modulation occurs are still being studied but are believed to involve both direct interactions with neurotransmitter systems and indirect effects on other signaling pathways.

3. The molecular structure of Delta THC allows it to bind more strongly to CB1 receptors than other cannabinoids.

One intriguing aspect that sets delta THC apart from other cannabinoids is its unique molecular structure. This structural difference enables it to bind more strongly to CB1 receptors, leading to a distinct psychoactive experience. While delta-9-THC shares similarities with delta-THC, the slight variation in their chemical structure results in different binding affinities and subsequent effects.

The enhanced affinity of delta THC for CB1 receptors contributes to its potency and may explain why it produces a milder high compared to delta-9-THC. This characteristic has made it an attractive option for individuals seeking a more subtle psychoactive experience or those who find the potent effects of delta-9-THC overwhelming.

Different Methods of Consuming Delta THC and Their Impact on the High

In the world of cannabis, there are various ways to consume delta-8 THC, each offering a unique experience. Whether you prefer the instant kick of inhalation methods, the long-lasting effects of edibles, or the balanced approach of sublingual administration, understanding how different consumption methods impact your high is essential.

Inhalation methods like vaping or smoking provide a quicker onset of effects but a shorter duration.

Inhalation methods such as vaping or smoking reign supreme. The reason behind their rapid onset lies in how quickly delta-8 THC enters your bloodstream through the lungs. As you inhale the vapor or smoke, the cannabinoids swiftly travel to your brain, resulting in a near-instantaneous effect.

Vaping is particularly popular among cannabis enthusiasts due to its discreet nature and customizable options. With vape pens and cartridges available in various flavors and potencies, users can easily control their dosage. Smoking traditional joints or using bongs also offers a similar quick onset but with a more classic feel.

However, it's important to note that while inhalation methods deliver fast results, they tend to have a shorter duration compared to other consumption techniques. The high from vaping or smoking delta-8 THC typically lasts for a couple of hours before gradually subsiding. This makes it ideal for those seeking immediate relief or looking for a quick burst of euphoria without committing to an extended experience.

Edibles offer a delayed onset but longer-lasting high due to slower absorption into the bloodstream.

If you're after an extended journey into blissful relaxation, edibles might be your best bet. These tasty treats infused with delta-8 THC take longer to kick in because they need time to be digested and absorbed by your body before reaching your bloodstream. Typically, it takes anywhere from 30 minutes up to two hours for the effects to fully manifest.

Once the delta-8 THC is metabolized, it produces a potent high that can last for several hours. This extended duration is due to the slow and steady release of cannabinoids into your system. Edibles provide a more gradual and sustained experience, allowing you to savor the effects without feeling overwhelmed by an intense peak.

From gummies and brownies to chocolates and beverages, there's an array of delicious options available. However, it's crucial to start with a low dosage and be patient since the onset can vary depending on factors such as metabolism and individual tolerance levels.

Sublingual administration provides a balance between quick onset and moderate duration.

For those seeking a middle ground between instant gratification and lasting effects, sublingual administration offers an appealing compromise. This method involves placing delta-8 THC tinctures or oils under your tongue, allowing them to be absorbed directly into your bloodstream through the thin tissues in that area.

Similar to inhalation methods, sublingual administration provides a relatively quick onset of effects. As the delta-8 THC bypasses digestion, it enters your bloodstream more rapidly than edibles but slower than inhalation methods. This means you can expect to feel the high within 15-30 minutes after application.

The duration of the high from sublingual consumption typically falls somewhere between inhalation methods and edibles.

Enhancing the Delta THC High: The Role of Terpenes

Terpenes play a significant role in shaping the flavor and aroma profile of cannabis. These aromatic compounds are found in various plants, including cannabis, and can interact synergistically with cannabinoids like delta THC to enhance their effects.

Terpenes and Their Impact on Cannabis

Terpenes are organic compounds responsible for the distinct smells and tastes associated with different strains of cannabis. They are also present in other plants such as lavender, citrus fruits, and pine trees. With over 200 different terpenes identified in cannabis alone, each strain offers a unique combination that contributes to its overall character.

Certain terpenes have been found to have notable effects. One such terpene is myrcene, which not only gives off an earthy aroma but also possesses sedative properties. When combined with delta THC, myrcene has the potential to amplify the relaxing aspects of the high.

Amplifying Relaxation with Myrcene

Myrcene is commonly found in India-dominant strains known for their calming effects. This terpene acts as a natural muscle relaxant and may help alleviate stress and promote sleep. When consumed alongside delta THC, myrcene's sedative properties can intensify the relaxation experienced during a high.

Imagine sinking into your favorite couch after taking a hit of your preferred delta 8 product infused with myrcene-rich cannabis oil. As you exhale, you feel the tension melting away from your body while waves of tranquility wash over you. The combination of myrcene and delta THC creates a harmonious blend that deepens relaxation beyond what either compound could achieve alone.

Synergistic Effects with Other Terpenes

While myrcene is a prominent example, there are several other terpenes that can enhance the delta THC high in different ways. Here are a few notable ones:

Limonene: This citrus-scented terpene can uplift mood and provide a boost of energy when combined with delta THC. It may counteract any potential sedative effects, resulting in a more balanced experience.

Pinene: As the name suggests, pinene has a distinct pine aroma. It is known for its potential to improve focus and alertness. When paired with delta THC, pinene can contribute to an uplifting and clear-headed high.

Caryophyllene: Found in black pepper and cloves, caryophyllene has anti-inflammatory properties and may help alleviate pain or discomfort during a delta 8 high. Its spicy notes add depth to the overall flavor profile as well.

By understanding the various terpenes present in cannabis strains and their unique characteristics, consumers can tailor their experiences according to their desired effects.

Finding the Right Balance: Dosing Delta THC for an Optimal High Start Low and Gauge Personal Sensitivity and Tolerance

It's essential to start with a low dose. This approach allows you to gauge your personal sensitivity and tolerance levels. Delta 8 THC can affect individuals differently, so beginning with a conservative dose is crucial.

By starting low, you give yourself the opportunity to assess how your body responds to this particular cannabinoid. It's worth noting that delta 8 THC typically produces a milder high compared to its more well-known counterpart, delta 9 THC. Nonetheless, everyone's reaction can vary.

Gradually Increase Dosage for Desired Effects

Once you've started with a low dose and familiarized yourself with how your body reacts, you can gradually increase your dosage until you achieve the desired effects. It's important not to rush this process; take your time in finding the optimal balance for an enjoyable experience.

As you increase the dosage, pay close attention to any potential side effects that may arise. While delta 8 THC is generally considered safe and well-tolerated by most individuals, excessive consumption can lead to adverse reactions such as anxiety or dizziness. By incrementally adjusting your dosage, you can mitigate these risks while still achieving the desired high.

Factors That Influence Optimal Dosing

Several individual factors play a role in determining what kind of high delta 8 THC will provide for each person. Understanding these factors will help guide you toward finding your ideal dosage:

Body Weight: Similar to other substances, body weight can influence how delta 8 THC affects an individual. Generally speaking, those with higher body weights may require slightly higher doses to achieve their desired results.

Metabolism: The speed at which your body metabolizes substances also plays a role in dosing considerations. Individuals with faster metabolisms may find that they require higher doses to achieve the desired effects.

Experience with Cannabis: Your previous experience with cannabis can impact how you respond to delta 8 THC. If you're a seasoned cannabis user, you may have developed a higher tolerance and require larger doses compared to someone new to the world of cannabinoids.

By taking these factors into account and adjusting your dosage accordingly, you'll be able to fine-tune your experience and discover the optimal high that delta 8 THC can offer.

Tips for a Safe and Enjoyable Delta THC Experience

It's important to prioritize safety and ensure that you have an enjoyable time. Whether you're new to delta 8 or a seasoned user, following these tips will help you make the most of your high while minimizing any potential risks or discomfort.

Choose reputable brands that provide lab-tested delta THC products to ensure quality and safety.

To have peace of mind during your delta 8 experience, it's crucial to choose products from reputable brands that prioritize quality and safety. Look for brands that conduct third-party lab testing on their products, as this ensures that they meet stringent standards for purity and potency. Lab reports can provide valuable information about the cannabinoid profile, contaminants, and overall quality of the product.

When purchasing delta 8 products, be cautious of counterfeit or low-quality options. These may not undergo proper testing and could contain harmful substances or inaccurate levels of delta 8. Opting for trusted brands will help you avoid any potential health risks associated with subpar products.

Consume in a comfortable and familiar environment to minimize potential anxiety or discomfort.

Creating the right setting is essential for a positive delta 8 experience. Find a comfortable space where you feel at ease, whether it's at home or with close friends in a familiar environment. This helps reduce anxiety or discomfort that can sometimes arise when using psychoactive substances.

Consider dimming the lights, playing relaxing music, or engaging in activities that bring you joy while under the influence of delta 8. By surrounding yourself with familiar elements and positive stimuli, you can enhance your overall enjoyment of the high.

Stay hydrated, have snacks on hand, and avoid operating heavy machinery while under the influence.

Delta 8 can cause dry mouth (also known as cottonmouth), so it's important to stay hydrated throughout your experience. Keep a bottle of water nearby to sip on regularly. Have some snacks readily available to satisfy any potential munchies that may arise.

While delta 8 can provide a delightful high, it's crucial to prioritize safety. Avoid operating heavy machinery or engaging in activities that require full concentration while under the influence. Delta 8 can affect your cognitive abilities and motor skills, so it's best to relax and enjoy the experience responsibly.

Best Delta 8 Products Everest Delta 8 Gummies

Everest Delta 8 Gummies are one of the top choices for those seeking a unique and enjoyable high. These gummies offer a delightful blend of flavor and potency, making them a favorite among cannabis enthusiasts. Each gummy is infused with high-quality delta 8 THC, providing users with a smooth and uplifting experience.

The Everest Delta 8 Gummies come in various delicious flavors, including peach, watermelon, and blueberry. This wide range of options allows users to find their preferred taste while enjoying the benefits of delta 8 THC. The gummies are carefully crafted to ensure consistent dosing, ensuring that each bite delivers the desired effect.

Budpop Delta 8 Gummies

For those looking for an exceptional delta 8 experience, Budpop Delta 8 Gummies are worth considering. These gummies combine premium ingredients with expert craftsmanship to provide users with an unforgettable high. Crafted using natural flavors and colors, Budpop gummies offer a burst of fruity goodness in every bite.

Budpop offers an array of tantalizing flavors like green apple, strawberry watermelon, and peach mango. With each piece containing precisely measured doses of delta 8 THC, users can easily control their intake for a tailored experience. Whether you're new to delta 8 or an experienced user, Budpop Delta 8 Gummies are sure to impress.

Exhale Wellness Delta 8 Gummies

Exhale Wellness is renowned for its commitment to quality products, and their Delta 8 Gummies live up to this reputation. Made from organically grown hemp extract and infused with pure delta 8 THC oil, these gummies deliver a potent yet smooth high that keeps users coming back for more.

What sets Exhale Wellness apart is its dedication to transparency and safety. Each batch of gummies undergoes rigorous third-party lab testing to ensure potency and purity. With flavors like pineapple, green apple, and strawberry, Exhale Wellness Delta 8 Gummies offer a delightful taste experience alongside their powerful effects.

3CHI Delta 8 Gummies

3CHI is a well-known brand in the delta 8 industry, and their Delta 8 Gummies have gained popularity for good reason. These gummies are made using high-quality hemp extract and infused with pure delta 8 THC distillate. The result is a product that delivers a smooth and uplifting high without any unwanted side effects.

With options like black raspberry, watermelon, and lemonade, 3CHI Delta 8 Gummies provide a range of flavors to suit different preferences. Each gummy contains precisely measured doses of delta 8 THC, allowing users to enjoy consistent effects every time they indulge.

Otterspace Delta 8 Gummies

If you're searching for an out-of-this-world delta 8 experience, look no further than Otterspace Delta 8 Gummies. These gummies are crafted with care using premium ingredients to provide users with an exceptional high. Each piece is infused with potent delta 8 THC oil for maximum effect.

Otterspace offers an assortment of delicious flavors such as mango, blue razz, and strawberry lemonade. These gummies not only deliver on taste but also on potency and consistency.

Conclusion: Understanding the High of Delta 8

In summary, understanding what kind of high to expect from Delta 8 THC is key before embarking on this journey. By being informed about its mind-altering effects, scientific properties, consumption methods, terpene influences, dosing strategies, safety precautions, and product selection criteria, you can make more informed decisions for an enjoyable experience.

So why wait? Explore the world of Delta 8 THC and discover the unique high it has to offer. Remember to prioritize your safety, start low, and experiment to find what works best for you.

FAQs Is Delta 8 THC legal?

Delta 8 THC is federally legal as long as it is derived from hemp and contains less than 0.3% Delta 9 THC. However, state laws may vary, so it's essential to check your local regulations before purchasing or using Delta 8 products.

How long does the high from Delta 8 THC last?

The duration of the high can vary depending on factors such as dosage, method of consumption, and individual metabolism. Generally, users can expect the effects to last anywhere from 2-6 hours.

Can I drive or operate machinery after consuming Delta 8 THC?

It is not recommended to drive or operate heavy machinery while under the influence of Delta 8 THC. The compound can impair cognitive function and motor skills, potentially compromising safety.

Are there any side effects associated with Delta 8 THC?

While generally well-tolerated, some users may experience side effects such as dry mouth, red eyes, increased heart rate, dizziness, or anxiety. These effects are typically mild and temporary.

Can I use Delta 8 THC for medical purposes?

Delta 8 THC may have potential therapeutic benefits; however, more research is needed to fully understand its medical applications. It's always advisable to consult with a healthcare professional before using any cannabis-derived product for medicinal purposes.

Weight-loss Drugs Like Wegovy, Ozempic May Raise Risk Of Complications Under Anesthesia, Doctors Say

Patients who take blockbuster drugs like Wegovy or Ozempic for weight loss may face life-threatening complications if they need surgery or other procedures that require empty stomachs for anesthesia. This summer's guidance to halt the medication for up to a week may not go far enough, either.

Some anesthesiologists in the U.S. And Canada say they've seen growing numbers of patients on the weight-loss drugs who inhaled food and liquid into their lungs while sedated because their stomachs were still full — even after following standard instructions to stop eating for six to eight hours in advance.

The drugs can slow digestion so much that it puts patients at increased risk for the problem, called pulmonary aspiration, which can cause dangerous lung damage, infections and even death, said Dr. Ion Hobai, an anesthesiologist at Massachusetts General Hospital in Boston.

"This is such a serious sort of potential complication that everybody who takes this drug should know about it," said Hobai, who was among the first to flag the issue.

Nearly 6 million prescriptions for the class of drugs that include Wegovy and Ozempic were written between January and May in the U.S. For people who don't have diabetes, according to Komodo Health, a health care technology company. The drugs induce weight loss by mimicking the actions of hormones, found primarily in the gut, that kick in after people eat. They also target signals between the gut and the brain that control appetite and feelings of fullness, and by slowing how fast the stomach empties.

In June, the American Society of Anesthesiologists issued guidance advising patients to skip daily weight-loss medications on the day of surgery and hold off on weekly injections for a week before any sedation procedures. Dr. Michael Champeau, the group's president, said the action was based on anecdotal reports of problems — including aspiration — from around the country.

It's not clear how many patients taking the anti-obesity drugs may be affected by the issue. But because the consequences can be so dire, Hobai and a group of colleagues decided to speak out. Writing in the Canadian Journal of Anesthesia, they called for the drug to be stopped for even longer — about three weeks before sedation.

That accounts for how long semaglutide, the active medication in Wegovy, remains in the body, said Dr. Philip Jones, a Mayo Clinic anesthesiologist who is also deputy editor-in-chief of the journal.

"When 90% of it is gone, which is after three weeks, hopefully everything should go back to normal," Jones said.

Champeau and Jones both acknowledged there's not enough evidence to say for certain how long semaglutide should be held to make anesthesia safe. Many patients won't see providers far enough in advance to stop the drug three weeks before procedures, Champeau noted.

Aspiration occurs in one of every 2,000 to 3,000 operations that require sedation, and almost half of patients who aspirate during surgery develop a related lung injury. But case reports show recent patients on semaglutide had problems even when they stopped food as long as 20 hours before their procedures.

"There's nothing that says if you fast twice as long, it will be OK," Champeau said.

Among the several reports detailing potentially serious problems was one of Hobai's patients, a 42-year-old man in Boston who recently began taking Wegovy, had to be intubated and suffered respiratory failure that put him in intensive care. He aspirated food that remained in his stomach despite fasting for 18 hours.

In Chapel Hill, North Carolina, a 31-year-old-woman on a low dose of Ozempic had fasted for 10 hours before a routine endoscopy prior to bariatric surgery last fall. The procedure had to be stopped because solid food remained in her stomach and she was at high risk for aspiration, the report said.

Since then, doctors have seen dozens of similar cases as use of the weight-loss medication has grown, said Dr. Elisa Lund, an anesthesiologist at the University of North Carolina at Chapel Hill School of Medicine. "It has exponentially increased," she said.

Hobai is completing a retrospective study of almost 200 patients taking semaglutide. While it'll be published later this year, the work so far appears to confirm a small study from Brazil, he said. In that study, about a quarter of patients taking semaglutide had residual food in their stomachs during procedures requiring sedation — even after stopping the drug for 10 days.

The American Society of Anesthesiologists advises doctors who are in doubt to treat patients who haven't paused the drug as if they have full stomachs, which can mean using different types of sedation protocols or delaying procedures, if possible. Jones added that research is urgently needed to update guidelines for doctors and patients.

Novo Nordisk, which makes Ozempic, Wegovy and similar drugs, said the firm's clinical trial and post-marketing safety data did not show that the medications led to aspiration. But the drugmaker noted that the medications are known to cause delayed emptying of the stomach and that the labels warn of possible gastrointestinal side effects.

Stopping the medications for three weeks can cause problems, too. Patients with diabetes will need another way to control their blood sugar and those seeking to lose weight may regain some, Hobai said.

Hobai suggests that people using Wegovy and similar drugs tell their doctors before sedation and discuss the risks and benefits.

"If you're taking this drug and you need an operation, you will need to have some extra precautions," he said.

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