Peanuts, shellfish or dairy can kill you: know the allergies, triggers, treatments and preventive measures
Preexisting Chronic Rhinosinusitis Linked With New Onset Asthma
Clinicians should be mindful of the transition from chronic rhinosinusitis to new onset asthma, while figuring out ways to prevent it.
"The clinical observation that chronic rhinosinusitis (CRS) and asthma commonly co-occur has been long known," explains Brian S. Schwartz, MD, MS. "This is thought to be due to shared inflammation in contiguous airways." According to Dr. Schwartz, however, no studies have employed the large sample sizes necessary to formally examine whether preexisting CRS is potentially causally linked with new onset asthma over time.
Dr. Schwartz and colleagues conducted a study, published in Allergy, to determine whether CRS is documented in patients without asthma and then assess the risk for new onset asthma in the following years. "This is the first step in developing new approaches for such patients, because if this risk is present over time, treatment for CRS could prevent the new onset of asthma," Dr. Schwartz says.
The study team used a large patient sample gathered from EHRs dating from 2008 to 2019. "[Our study] required a large patient sample since we have to remove all people with prevalent asthma from the analysis," Dr. Schwartz explains, adding that there were more than 43,000 such patients. They conducted a retrospective cohort study of people with and without CRS and looked for the new development of asthma over time, comparing more than 35,000 patients who developed asthma with more than 890,000 who did not.
Younger Women More Likely to Have New Onset AsthmaTo adjust for confounding variables (eg, contact with the health system, sociodemographic, comorbidities), the researchers used complementary log-log regression.
The study team hypothesized that CRS based on diagnoses would have higher sensitivity in case finding, and that CRS based on sinus CT scans would have higher specificity. "We identified new onset asthma with diagnoses or medications for asthma in [people] who did not previously have a record of either," Dr. Schwartz says. "We observed that both methods of identifying CRS were associated with increased risk for new onset asthma, with a 1.5-fold increased risk for CRS based on diagnoses and 2.2-fold increased risk for CRS based on positive sinus CT scans." Both CRS definitions were linked (HR, 95% CI) with new onset asthma, with 2.21 (1.93-2.54) and 1.48 (1.38-1.59) for CRS based on sinus CT scans and two diagnoses, respectively.
Individuals with new onset asthma tended to be female (69.6%) and younger (mean [SD] age 45.9 [17.0]), the researchers note. New onset asthma was uncommonly observed in people with a history of sinus surgery.
Future Research Should Seek Ways to Prevent Asthma Onset"We found that the elevated risk for new onset asthma after CRS diagnosis persists for over 6 years (Table)" Dr. Schwartz says. "We were worried that the increased risk could be due to more careful case finding for asthma after a diagnosis of sinus disease. However, the fact that the elevated risk persists for much longer suggests that the associations are not due to this concern."
Dr. Schwartz and colleagues concur that people with CRS can develop new onset asthma over time. "The elevated risk is more than two-fold for CRS based on sinus CT scan," Dr. Schwartz notes. "Clinicians should be vigilant about this transition—many already are—and we should figure out how to prevent it if possible." Therefore, he adds, the next logical step is to conduct prospective studies to determine whether, and how, treatment of CRS could prevent the onset of asthma.
Alkem Laboratories Launches "Stop Sneeze To Wheeze" Campaign
Read by: 100 Industry Professionals
The "Stop Sneeze to Wheeze" campaign will coordinate multiple activities and programmes across the country to meet its objectives. There are over 600 camps, 200–300 CME (Continuing Medical Education) sessions, 60 TV shows, and 1000 awareness campaigns among them. Alkem Laboratories hopes to educate the public and healthcare professionals through these programmes to enable early detection and appropriate treatment.
Allergic Rhinitis, commonly known as hay fever, is an inflammatory condition that affects the nasal passages. It is triggered by allergens such as pollen, dust mites, pet dander, and mold spores. If left untreated, Allergic Rhinitis can progress to asthma, a chronic respiratory condition characterized by airway inflammation and heightened sensitivity to triggers.The coexistence of Allergic Rhinitis and Asthma presents unique challenges, as these conditions interact and exacerbate each other's symptoms. Allergic Rhinitis can worsen asthma symptoms, and uncontrolled asthma can intensify Allergic Rhinitis symptoms, creating a distressing cycle of respiratory difficulties that significantly impact an individual's quality of life.
Sudipta Roy, President, Head - Acute business at Alkem Laboratories Ltd, said, "The incidence of asthma and Allergic Rhinitis is on the rise within the general population, with a significant number of newly diagnosed patients experiencing both upper and lower airway symptoms. Recent estimates suggest that approximately 60 to 78% of individuals diagnosed with asthma also have concurrent Allergic Rhinitis."Subscribe to our newsletter to get latest insights & analysis.
Canada Air Quality Professionals Address The Role Of Air Filters In Preventing Airborne Allergy Symptoms
In a new resource, air quality professionals from Camfil explain the prevalence of airborne allergies in Canada and how air filters can mitigate symptoms.
Canada Air Quality Professionals Address the Role of Air Filters in Preventing Airborne Allergy Symptoms
In a new resource, air quality professionals from Camfil explain the prevalence of airborne allergies in Canada and how air filters can mitigate symptoms.
2700 Steeles Avenue W, Concord, ON L4K 3C8, July 03, 2023 (GLOBE NEWSWIRE) -- Toronto, Ontario — Airborne allergies are usually associated with springtime, but due to increasingly longer pollen seasons and year-round allergens such as pet dander, dust, and mold spores, allergies can affect people in Canada year-round. According to the World Health Organization, allergies are the fourth leading cause of chronic illness, with up to a third of adults experiencing allergic rhinitis, an immune system response to airborne allergens.
In a new resource, air quality professionals from Camfil explain the prevalence of airborne allergies in Canada and how air filters can mitigate symptoms.
"One of the quickest ways to deal with symptoms of allergies, is to use a high-quality, high-efficiency air filter in your home or building," says air quality expert Berni Baier at Camfil, Canada, "High-quality air filters help remove pollen, PM2.5, PM1, pet dander, dust mites, mould spores,, and other harmful particles from the air. These filters trap particles in dense media and prevents them from circulating in the air."
The resource covers a range of topics related to preventing allergy symptoms in Canada, including:
What are the most common allergy triggers for Canadians?
What are the symptoms of airborne and seasonal allergies?
What strategies lessen allergy symptoms?
How can air filters prevent seasonal allergy symptoms?
What are the best air filters for people with allergies?
Why is it important to improve indoor air quality?
Read the full resource on improving allergy symptoms with premium Canadian air filters here.
About Camfil Canada Clean Air Solutions
For more than half a century, Camfil has been helping people breathe cleaner air. As a leading manufacturer of premium clean air solutions, we provide commercial and industrial systems for air filtration and air pollution control that improve worker and equipment productivity, minimize energy use, and benefit human health and the environment. Read more about Camfil Canada.
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Media Contact:
Phillip Ilijevski
Camfil Canada Inc.
T: 437-929-1161
E: Phillip.Ilijevski@camfil.Com
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